Research Article
COL11A1 is Downregulated by miR-339-5p and Promotes Colon Carcinoma Progression
Figure 3
MiR-339-5p binds COL11A1 in colon carcinoma cells. (a) Volcano plot of differential miRNAs from TCGA-COAD. (b) Venn diagram of predicted miRNAs of COL11A1 and differential miRNAs. (c) Pearson correlation analysis of COL11A1 and its predicted upstream miRNAs. (d) Violin plot of miR-339-5p expression from TCGA database. (e) MiR-339-5p expression in NCM460, HCT116, Caco205, SW620, and SW480 cell lines. (f) Bioinformatics predicted binding sites of miR-339-5p and COL11A1. (g) Relative luciferase activity of different transfection group. (h) COL11A1 mRNA expression level in colon carcinoma SW620 and SW480 after overexpressing miR-339-5p. , , .
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