Research Article

The Impact of Serum Parameters Associated with Kidney Function on the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients Undergoing Radical Surgery

Table 1

Comparison between the normal BUN group and the abnormal BUN group.

CharacteristicsNormal BUN (1937)Abnormal BUN (110) value

Age, year63.0 (20.0–94.0)70.0 (38.0–91.0)<0.01
Sex<0.01
 Male1124 (58.0%)88 (80.0%)
 Female813 (42.0%)22 (20.0%)
BMI, kg/m222.8 (14.2–37.3)22.0 (15.8–33.7)0.054
Smoking726 (37.5%)59 (5act3.6%)0.001
Drinking590 (30.5%)48 (43.6%)0.004
Hypertension479 (24.7%)50 (45.5%)<0.01
T2DM231 (11.9%)25 (22.7%)0.001
CHD69 (3.6%)7 (6.4%)0.124
Open surgery189 (9.8%)13 (11.8%)0.481
Tumor location0.406
 Colon853 (44.0%)44 (40.0%)
 Rectum1084 (56.0%)66 (60.0%)
TNM stage0.582
 I391 (20.2%)20 (18.2%)
 II795 (41.0%)40 (36.4%)
 III660 (34.1%)44 (40.0%)
 IV91 (4.7%)6 (5.5%)
Tumor size0.881
 <5 cm1141 (58.9%)64 (58.2%)
 ≥5 cm796 (41.1%)46 (41.8%)
Operation time (min)215.0 (45.0–695.0)221.5 (75.0–540.0)0.530
Blood loss (mL)50.0 (5.0–3500.0)80.0 (5.0–2200.0)0.335
Hospital stay (day)9.0 (2.0–269.0)10.0 (4.0–54.0)0.002
Overall complications399 (20.6%)37 (33.6%)0.001
Major complications46 (2.4%)3 (2.7%)0.745

Variables are expressed as the median and range, n (%), -value <0.05. Abbreviations: BUN, blood urea nitrogen; T2DM, type 2 diabetes mellitus; BMI, body mass index; CHD, coronary heart disease.