The Impact of Serum Parameters Associated with Kidney Function on the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients Undergoing Radical Surgery
Table 3
Comparison between the normal CysC group and the abnormal CysC group.
Characteristics
Normal CysC (1627)
Abnormal CysC (420)
value
Age, year
61.0 (20.0–91.0)
71.5 (37.0–94.0)
<0.01
Sex
<0.01
Male
909 (55.8%)
303 (72.1%)
Female
718 (44.1%)
117 (27.9%)
BMI, kg/m2
22.8 (14.7–37.3)
22.6 (14.2–35.4)
0.762
Smoking
585 (35.9%)
200 (47.6%)
<0.01
Drinking
486 (29.9%)
152 (36.2%)
0.013
Hypertension
354 (21.8%)
175 (41.7%)
<0.01
T2DM
189 (11.6%)
67 (16.0%)
0.017
CHD
48 (3.0%)
28 (6.7%)
<0.01
Open surgery
141 (8.7%)
61 (14.5%)
<0.01
Tumor location
0.655
Colon
717 (44.1%)
180 (42.9%)
Rectum
910 (55.9%)
240 (57.1%)
TNM stage
0.613
I
329 (20.2%)
82 (19.5%)
II
667 (41.0%)
168 (40%)
III
559 (34.3%)
145 (34.5%)
IV
72 (4.4%)
25 (6.0%)
Tumor size
0.141
<5 cm
971 (59.7%)
234 (55.7%)
≥5 cm
656 (40.3%)
186 (44.3%)
Operation time (min)
215.0 (45.0–695.0)
220.0 (86.0–560.0)
0.454
Blood loss (mL)
50.0 (5.0–3500.0)
70.0 (5.0–2200.0)
0.088
Hospital stay (day)
9.0 (3.0–70.0)
10.0 (2.0–269.0)
<0.01
Overall complications
307 (18.9%)
129 (30.7%)
<0.01
Major complications
30 (1.8%)
19 (4.5%)
0.001
Variables are expressed as the median and range, n (%), -value <0.05. Abbreviations: CysC, cystatin C; T2DM, type 2 diabetes mellitus; BMI, body mass index; CHD, and coronary heart disease.