Research Article

The Impact of Serum Parameters Associated with Kidney Function on the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients Undergoing Radical Surgery

Table 3

Comparison between the normal CysC group and the abnormal CysC group.

CharacteristicsNormal CysC (1627)Abnormal CysC (420) value

Age, year61.0 (20.0–91.0)71.5 (37.0–94.0)<0.01
Sex<0.01
 Male909 (55.8%)303 (72.1%)
 Female718 (44.1%)117 (27.9%)
BMI, kg/m222.8 (14.7–37.3)22.6 (14.2–35.4)0.762
Smoking585 (35.9%)200 (47.6%)<0.01
Drinking486 (29.9%)152 (36.2%)0.013
Hypertension354 (21.8%)175 (41.7%)<0.01
T2DM189 (11.6%)67 (16.0%)0.017
CHD48 (3.0%)28 (6.7%)<0.01
Open surgery141 (8.7%)61 (14.5%)<0.01
Tumor location0.655
 Colon717 (44.1%)180 (42.9%)
 Rectum910 (55.9%)240 (57.1%)
TNM stage0.613
 I329 (20.2%)82 (19.5%)
 II667 (41.0%)168 (40%)
 III559 (34.3%)145 (34.5%)
 IV72 (4.4%)25 (6.0%)
Tumor size0.141
 <5 cm971 (59.7%)234 (55.7%)
 ≥5 cm656 (40.3%)186 (44.3%)
Operation time (min)215.0 (45.0–695.0)220.0 (86.0–560.0)0.454
Blood loss (mL)50.0 (5.0–3500.0)70.0 (5.0–2200.0)0.088
Hospital stay (day)9.0 (3.0–70.0)10.0 (2.0–269.0)<0.01
Overall complications307 (18.9%)129 (30.7%)<0.01
Major complications30 (1.8%)19 (4.5%)0.001

Variables are expressed as the median and range, n (%), -value <0.05. Abbreviations: CysC, cystatin C; T2DM, type 2 diabetes mellitus; BMI, body mass index; CHD, and coronary heart disease.