The Impact of Serum Parameters Associated with Kidney Function on the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients Undergoing Radical Surgery
Table 4
Univariate and multivariate analyses of overall survival.
Risk factors
Univariate analysis
Multivariate analysis
HR (95% CI)
value
HR (95% CI)
value
Age (years)
1.039 (1.028–1.050)
<0.01
1.041 (1.029–1.053)
<0.01
Sex (female/male)
0.716 (0.558–0.919)
0.009
0.818 (0.598–1.119)
0.208
BMI (kg/m2)
0.969 (0.933–1.007)
0.105
T2DM (yes/no)
1.303 (0.925–1.836)
0.130
Tumor site (colon/rectum)
1.011 (0.796–1.283)
0.931
Tumor stage (IV/III/II/I)
2.123 (1.823–2.473)
<0.01
2.134 (1.828–2.491)
<0.01
Smoking (yes/no)
1.356 (1.070–1.717)
0.012
1.211 (0.899–1.630)
0.207
Drinking (yes/no)
1.190 (0.929–1.525)
0.169
Hypertension (yes/no)
0.975 (0.739–1.285)
0.855
CHD (yes/no)
1.590 (0.928–2.722)
0.091
Tumor size (≥5 cm/<5 cm)
1.451 (1.147–1.837)
0.002
1.231 (0.972–1.560)
0.085
BUN (abnormal/normal)
1.348 (0.855–2.125)
0.198
UA (abnormal/normal)
0.712 (0.485–1.046)
0.083
CysC (abnormal/normal)
1.441 (1.108–1.875)
0.006
0.860 (0.645–1.147)
0.304
Overall complications (yes/no)
1.682 (1.311–2.158)
<0.01
1.499 (1.166–1.928)
0.002
-value <0.05. Abbreviations: BUN, blood urea nitrogen; UA, uric acid; CysC, cystatin C; HR, hazard ratio; CI, confidence interval; BMI, body mass index; T2DM, and type 2 diabetes mellitus.
