The Impact of Serum Parameters Associated with Kidney Function on the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients Undergoing Radical Surgery
Table 5
Univariate and multivariate analyses of disease-free survival.
Risk factors
Univariate analysis
Multivariate analysis
HR (95% CI)
value
HR (95% CI)
value
Age (years)
1.026 (1.017–1.036)
<0.01
1.026 (1.016–1.037)
<0.01
Sex (female/male)
0.797 (0.639–0.994)
0.044
0.904 (0.682–1.199)
0.484
BMI (kg/m2)
0.992 (0.959–1.026)
0.634
T2DM (yes/no)
1.157 (0.843–1.589)
0.366
Tumor site (colon/rectum)
1.024 (0.827–1.268)
0.829
Tumor stage (IV/III/II/I)
2.053 (1.791–2.352)
<0.01
2.053 (1.788–2.357)
<0.01
Smoking (yes/no)
1.288 (1.041–1.594)
0.020
1.189 (0.906–1.561)
0.212
Drinking (yes/no)
1.206 (0.965–1.507)
0.100
Hypertension (yes/no)
1.021 (0.800–1.303)
0.868
CHD (yes/no)
1.421 (0.860–2.348)
0.170
Tumor size (≥5 cm/<5 cm)
1.340 (1.084–1.656)
0.007
1.134 (0.917–1.404)
0.247
BUN (abnormal/normal)
1.115 (0.717–1.734)
0.629
UA (abnormal/normal)
0.839 (0.608–1.159)
0.287
CysC (abnormal/normal)
1.357 (1.068–1.723)
0.012
0.941 (0.725–1.223)
0.651
Overall complications (yes/no)
1.542 (1.227–1.937)
<0.01
1.440 (1.144–1.814)
0.002
value <0.05. Abbreviations: BUN, blood urea nitrogen; UA, uric acid; CysC, cystatin C; HR, hazard ratio; CI, confidence interval; BMI, body mass index; T2DM, and type 2 diabetes mellitus.
