Liver Assessment in Patients with Ataxia-Telangiectasia: Transient Elastography Detects Early Stages of Steatosis and Fibrosis

Table 1

Patients’ characteristics.

Parameter	Group 1 (n = 21)	Group 2 (n = 10)	value
Sex	9♀/12♂	5♀/5♂
Age (years)	6.5 ± 2.8	19.6 ± 3.5	<0.0001
CAP (dB/m)	174.7 ± 45.1	302.2 ± 57.7	<0.001
LSM (kPa)	4.6 ± 0.9	9 ± 6.9	<0.001
AFP (ng/mL)	313.4 ± 267.2	540.8 ± 275.8	<0.05
CRP (mg/dL)	0.2 ± 0.4	0.5 ± 0.8	n.s.
AST (U/L)	37.8 ± 7.9	49.8 ± 15.2	<0.05
ALT (U/L)	25.1 ± 9.6	71.6 ± 25.8	<0.001
GGT (U/L)	13.2 ± 4.5	123.7 ± 99.6	<0.0001

Mean values ± SD are shown; n.s. = not significant.