Research Article

Analysis of Complications and Risk Factors Other than Bleeding before and after Endoscopic Treatment of Esophagogastric Variceal Bleeding in Patients with Liver Cirrhosis

Table 3

Univariate and multivariate analyses of factors affecting the occurrence of portal vein thrombosis and/or cavernous lesions in liver cirrhosis patients during the late follow-up (Cox regression analysis).

CharacteristicsSingle-factor analysisMultifactor analysis
HR95% CIHR95% CI

Gender: 1 male and 2 female0.520.31–0.890.0170.8840.444–1.760.725
Age (years old)0.9730.954–0.9920.0061.0720.644–1.7840.79
Time of cirrhosis was found (years)1.0041.001–1.0060.0051.0041.001–1.0070.022
The square of the height of the kg. weight1.0350.993–1.0790.103
Blood pressure. Systolic pressure 90–139 vs. 902.030.64–6.450.229
Blood pressure. Systolic blood pressure 140–159 vs. 902.070.57–7.540.269
Blood pressure. Systolic blood pressure 160–179 vs. 9000-Inf0.997
Blood pressure. Systolic blood pressure greater than 180 vs. 9000-Inf0.998
Heart rate. 60–100 beats per minute vs. less than 60 beats per minute2.80.39–20.140.306
Heart rate. Over 100 beats per minute vs. less than 60 beats per minute4.470.57–34.890.154
Spider nevus of liver and palm (none)1.020.62–1.670.949
History of splenectomy (none)0.620.38–10.0491.0240.58–1.8080.935
Education level primary school vs. none1.220.56–2.670.62
Education level: junior high vs. none1.690.77–3.70.192
Education level: high school vs. none1.940.86–4.40.111
University education or above vs. none1.560.33–7.370.576
Smoking (yes)0.990.6–1.640.965
Drink alcohol (yes)0.980.63–1.530.932
Antiviral drug use. No vs. yes0.5950.391–0.9070.0160.9170.533–1.5760.753
Whether to take beta blockers. No vs. yes1.10.27–4.460.897
Etiology of cirrhosis: posthepatitic C vs. posthepatitic B0.510.12–2.090.3491.110.248–4.9640.891
Etiology of cirrhosis. Alcoholic cirrhosis vs. posthepatitis B cirrhosis0.410.18–0.960.0450.630.239–1.6620.35
Etiology of cirrhosis. Mixed cirrhosis vs. posthepatitis B cirrhosis0.720.36–1.470.370.7790.347–1.7480.545
Etiology of cirrhosis. Autoimmune cirrhosis. vs. posthepatitis B cirrhosis0.380.09–1.570.1810.5630.114–2.7880.482
Etiology of cirrhosis: cholestatic cirrhosis vs. posthepatitis B cirrhosis0.120.03–0.510.0040.2010.043–0.9380.041
Schistosomiasis is the cause of cirrhosis00-Inf0.99500–1.8 E+2710.973
Etiology of cirrhosis. Unknown cause vs. posthepatitis B cirrhosis1.020.56–1.830.9581.1020.537–2.2640.791
Diabetes (yes)1.440.8–2.590.225
HBV titer PCR.IUML. 1. Negative. 1000ium.2. Positive. 1000 IUml.l0.790.35–1.820.583
Degree of esophageal and fundus varices. Heavy vs. medium0.6990.431–1.1320.146
The treatment of varicose veins. Sclerotherapy vs. ligation0.910.55–1.480.694
The treatment of varicose veins. Tissue glue vs. ligation1.520.47–4.930.486
The treatment of varicose veins. Combination therapy vs. ligation1.220.7–2.110.486
Grading of child0.970.89–1.050.438
Whether it is complicated with liver cancer (1) yes and (2) no0.920.4–2.080.836
Whether there is portal hypertensive gastropathy (1) yes and (2) no0.840.42–1.680.63
D-dimer1.020.95–1.090.615
International standardized ratio (INR)1.10.5–2.420.805
Prothrombin time (PT)1.020.95–1.10.531
Alanine aminotransferase (ALT)11-10.758
Aspartic acid aminotransferase (AST)1445620.358
Aspartate aminotransferase (AST). Platelets (PLT). APRI0.950.82–1.090.47
Albumin (ALB)1.010.98–1.030.568
Gamma transglutaminase0.9970.994–10.0330.9980.993–1.0020.301
Alkaline phosphatase (ALP)0.9970.994–10.02210.995–1.0050.911
Total bilirubin (TBil)0.990.97–10.052
Creatinine (Cr)10.99–10.335
The urea0.990.93–1.040.635
Glomerular filtration rate (GFR)1.011–1.020.103
Triglyceride trifat0.530.24–1.190.125
Cholesterol0.990.82–1.190.886
Blood calcium1.170.35–3.890.8
Serum sodium10.93–1.070.937
Neutrophils (Neu)0.950.86–1.050.306
Lymphocyte count (LYM)0.970.73–1.290.846
Neutrophils. Ratio of neutrophils to lymphocytes0.970.91–1.040.422
White blood cell count0.970.91–1.040.412
Hemoglobin (Hb)11–1.010.269
Platelet count (PLT)11–10.15
Erythrocyte distribution width. RDW. CV0.990.92–1.070.781
CLIF-C Ads0.930.881–0.9810.0080.9540.898–1.0140.13

CLIF-C Ads, CLIF consortium acute decompensation score; HR, hazard ratio; CI, confidence interval.