Analysis of Complications and Risk Factors Other than Bleeding before and after Endoscopic Treatment of Esophagogastric Variceal Bleeding in Patients with Liver Cirrhosis

Table 4

Univariate and multivariate analyses of factors affecting the occurrence of infection in liver cirrhosis patients during the late follow-up (Cox regression analysis).

Characteristics	Single-factor analysis			Multifactor analysis
	HR	95% CI		HR	95% CI
Gender: 1 male and 2 female	1.04	0.62–1.75	0.88
Age (years old)	1.02	1–1.04	0.09
Time of cirrhosis was found (years)	1	1-1	0.685
The square of the height of the kg weight	1.2	0.6–2.38	0.606
Blood pressure. Systolic pressure 90–139 vs. 90	0.73	0.29–1.83	0.508
Blood pressure. Systolic blood pressure 140–159 vs. 90	0.56	0.17–1.84	0.338
Blood pressure. Systolic blood pressure 160–179 vs. 90	1.53	0.29–7.91	0.614
Blood pressure. Systolic blood pressure greater than 180 vs. 90	0	0-Inf	0.995
Heart rate. 60–100 beats per minute vs. less than 60 beats per minute	1.13	0.28–4.62	0.866
Heart rate. Over 100 beats per minute vs. less than 60 beats per minute	0.67	0.12–3.65	0.642
Liver and palm spider nevus (yes)	0.85	0.5–1.45	0.543
History of splenectomy (yes)	0.79	0.45–1.38	0.407
Education level: primary school vs. none	1.12	0.5–2.49	0.78
Education level: junior high vs. none	1.4	0.63–3.11	0.414
Education level high school vs. none	0.67	0.26–1.74	0.407
University education or above vs. none	0	0-Inf	0.995
Smoking (yes)	1.34	0.72–2.5	0.355
Drink alcohol (yes)	0.89	0.54–1.46	0.636
Antiviral drug use. No vs. yes	1.06	0.65–1.73	0.817
Whether to take beta blockers. No vs. yes	1.99	0.28–14.41	0.494
Etiology of cirrhosis: posthepatitic C vs. posthepatitic B	2	0.61–6.57	0.253
Etiology of cirrhosis. Alcoholic cirrhosis vs. posthepatitis B cirrhosis	1.67	0.79–3.52	0.177
Etiology of cirrhosis. Mixed cirrhosis vs. posthepatitis B cirrhosis	1.41	0.65–3.07	0.39
Etiology of cirrhosis. Autoimmune cirrhosis. vs. posthepatitis B cirrhosis	1.9	0.67–5.41	0.227
Etiology of cirrhosis: cholestatic cirrhosis vs. posthepatitis B cirrhosis	1.73	0.79–3.77	0.17
Schistosomiasis is the cause of cirrhosis	0	0-Inf	0.995
Etiology of cirrhosis. Unknown cause vs. posthepatitis B cirrhosis	1.02	0.47–2.24	0.951
Diabetes (yes)	0.86	0.48–1.55	0.621
HBV titer PCR.IUML. 1. Negative. 1000ium.2. Positive.1000 IUml.l	0.93	0.37–2.32	0.881
Degree of esophageal and fundus varices. Heavy vs. medium	0.24	0.08–0.77	0.016	0.203	0.062–0.667	0.009
The treatment of varicose veins. Sclerotherapy vs. ligation	0.79	0.44–1.4	0.414
The treatment of varicose veins. Tissue glue vs. ligation	1.1	0.26–4.61	0.897
The treatment of varicose veins. Combination therapy vs. ligation	1.27	0.69–2.33	0.44
Grading of child	1.1	0.99–1.22	0.08
Whether it is complicated with liver cancer. (1) yes and (2) no	0.93	0.41–2.13	0.867
Whether there is portal hypertensive gastropathy (1) yes and (2) no	1.69	0.61–4.63	0.31
D-dimer	1.09	1.01–1.17	0.025	1.093	1.002–1.193	0.046
International standardized ratio (INR)	1.27	0.5–3.24	0.612
Prothrombin time (PT)	1.04	0.96–1.12	0.371
Alanine aminotransferase (ALT)	1	1-1	0.553
Aspartic acid aminotransferase (AST)	1	1-1	0.495
Aspartate aminotransferase (AST). Platelets (PLT). APRI	0.93	0.79–1.11	0.443
Albumin (ALB)	0.96	0.92–0.99	0.022	0.979	0.932–1.03	0.416
Gamma transglutaminase	1	1-1	0.715
Alkaline phosphatase (ALP)	1	1-1	0.407
Total bilirubin (TBil)	1	0.98–1.01	0.841
Creatinine (Cr)	1	0.99–1.01	0.487
The urea	1.04	0.99–1.09	0.127
Glomerular filtration rate (GFR)	1	0.99–1.01	0.744
Triglyceride trifat	1	0.37–2.73	0.998
Cholesterol	0.85	0.61–1.2	0.355
Blood calcium	0.18	0.08–0.43	<0.001	0.497	0.117–2.11	0.343
Serum sodium	1.06	0.97–1.15	0.184
Neutrophils (Neu)	1.01	0.93–1.09	0.866
Lymphocyte count (LYM)	0.97	0.7–1.34	0.85
Neutrophils. Ratio of neutrophils to lymphocytes	1.01	0.96–1.06	0.78
White blood cell count	1	0.94–1.07	0.948
Hemoglobin (Hb)	0.99	0.98–1	0.047	0.997	0.983–1.011	0.997
Platelet count (PLT)	1	1-1	0.731
Erythrocyte distribution width. RDW. CV	1.04	0.96–1.13	0.315
CLIF-C Ads	1.043	0.976–1.114	0.21

CLIF-C Ads, CLIF consortium acute decompensation score; HR, hazard ratio; CI, confidence interval.