Research Article
Effect of COVID-19 Pandemic-Related Delays in Chemoembolization on the Survival of Patients with Hepatocellular Carcinoma
Table 3
Baseline characteristics of the study participants who underwent repeated TACE.
| Factors | Prelockdown group (n = 87) | Lockdown group (n = 58) | value |
| Age, years, mean ± SD | 63.9 ± 10.3 | 65.3 ± 8.8 | 0.406 | Sex, male, n (%) | 64 (73.6) | 45 (77.6) | Liver disease etiology, n (%) | 0.225 | HBV | 48 (55.2) | 31 (53.4) | HCV | 25 (28.7) | 10 (17.2) | HBV + HCV | 2 (2.3) | 1 (1.7) | Alcohol | 4 (4.6) | 5 (8.6) | Others | 8 (9.2) | 11 (19) | Severity of liver disease, n (%) | 0.079 | Child–Pugh A | 63 (72.4) | 50 (86.2) | Child–Pugh B | 24 (27.6) | 8 (13.8) | BCLC stage, n (%) | 0.610 | A | 10 (11.5) | 10 (17.2) | B | 65 (74.7) | 41 (70.7) | C | 12 (13.8) | 7 (12.1) | AFP (ng/mL), n (%) | 0.393 | ≤200 | 64 (73.6) | 38 (65.5) | >200 | 23 (26.4) | 20 (34.5) | ALT (U/L), median (IQR) | 33.0 (21.5–45.0) | 30.5 (25.0–41.0) | 0.565 | AST (U/L), median (IQR) | 55.0 (35.5–76.5) | 44.5 (33.0–71.8) | 0.218 | Total bilirubin (mg/dL), median (IQR) | 0.8 (0.5–1.4) | 0.9 (0.5–1.3) | 0.548 | Albumin (g/dL), mean ± SD | 3.6 ± 0.6 | 3.4 ± 0.6 | 0.165 | Platelet count (×103/mm3), median (IQR) | 112.5 (71.2–149.5) | 96 (71.5–153.5) | 0.584 | Size of main tumor (cm), median (range) | 3.2 (1.1–12.8) | 3.0 (1.1–16.0) | 0.266 | Number of tumors, n (%) | 0.793 | 1–3 | 46 (52.9) | 34 (58.6) | 4-5 | 17 (19.5) | 10 (17.2) | >5 | 24 (27.6) | 14 (24.1) | Vascular invasion, n (%) | 0.781 | Absent | 53 (91.4) | 77 (88.5) | Present | 5 (8.6) | 10 (11.5) | Previous TACE sessions, median (IQR) | 2 (1–5) | 2 (1–4) | 0.756 | Time interval (days), mean ± SD | 63.5 ± 25.2 | 76.7 ± 32.9 | 0.007∗ | Hospitalization (days), median (IQR) | 3 (3–3.5) | 3 (3–3) | 0.682 |
|
|
TACE, transarterial chemoembolization; HBV, hepatitis B virus; HCV, hepatitis C virus; BCLC, Barcelona Clinic Liver Cancer; AFP, alpha-fetoprotein; ALT, alanine transaminase; IQR, interquartile range; AST, aspartate transaminase; SD, standard deviation.
|