Role of Probiotics in Helicobacter pylori Eradication: Lessons from a Study of Lactobacillus reuteri Strains DSM 17938 and ATCC PTA 6475 (Gastrus®) and a Proton-Pump Inhibitor

Figure 3

Hp-treatment nomogram showing theoretical cure rates with 14-day triple therapy with standard dose PPI (e.g., 40 mg of omeprazole b.i.d.) in the absence and presence of resistance. This would increase the population cure rate in the “all clarithromycin resistant” subgroup (PPI + amoxicillin) from 20 to 40%. Based on an increase in the cure rate of 12% with probiotic, the addition of probiotic adjuvant therapy would increase the point where the cure rates fell below 90% from approximately 13% (solid line) to 33% (dotted line).