Blood and Bronchoalveolar Lavage Fluid Metagenomic Next-Generation Sequencing in Pneumonia

Table 1

Baseline characteristics of 39 patients.

Characteristic	Value (median (IQRs) or no. (%))
Age (years)
Years	56 (34, 66)
Distribution
≤18 years old	4 (10.3%)
19–40 years old	6 (15.3%)
41–60 years old	12 (30.8%)
>60 years old	17 (43.6%)
Male sex	30 (76.9%)
Onset symptoms
Dyspnea	21 (53.8%)
Fever	26 (66.7%)
Cough	30 (76.9%)
Hemoptysis	3 (7.7%)
Inflammation biomarker
WBC (10^9/L)	10.5 (8.5, 14.8)
NEU (%)	85.8 (77.7, 90.3)
Lym (10^9/L)	0.78 (0.59, 1.47)
PCT (ng/ml)	0.81 (0.17, 2.3)
CRP (mg/L)	122 (34, 187)
ESR (mm/h)	57 (29, 84)
Comorbidity
Diabetes mellitus	7 (17.9%)
Chronic kidney disease	9 (23.1%)
Liver disease	4 (10.3%)
Immunocompromised
Solid organ transplantation	2 (5.1%)
Malignancies	1 (2.6%)
Chemotherapy	3 (7.7%)
Immunosuppression for rheumatological diseases	4 (10.3%)
Immunosuppression for chronic kidney disease	4 (10.3%)
ICU admission	35 (89.7%)
Severity score
APACHE II	14.0 (7.8, 21.5)
SOFA	4.5 (2.0, 9.0)
Disease-onset to sampling time (days)	22 (12, 36)
Length of stay (days)
In hospital	16 (8, 39)
In ICU	12 (4, 30)

Abbreviations: WBC, white blood cells; NEU%, percentage of neutrophil; Lym, lymphocytes; PCT, procalcitonin; CRP, C reactive protein; ESR, erythrocyte sedimentation rate; APACHE, acute physiology and chronic health evaluation scoring system; SOFA, sequential organ failure assessment; ICU, intensive care unit.