An Immunoinformatics Study to Predict Epitopes in the Envelope Protein of SARS-CoV-2

Table 2

List of CTL epitopes that have good combined score and are antigenic, nonallergic, and immunogenic, and bind with an affinity IC50 value of less than 200 with the MHC-I alleles.

Epitopes	Position in sequence	Combined score	Interaction of MHC-I allele with an affinity IC50 value of <200	Immunogenicity	Antigenic	Allergen	Toxic	Population coverage (%)	Binding score (kcal/mol) of epitopes with MHC-I
FLAFVVFLL	20	1.44	HLA-A02:01; HLA-A02:06; HLA-B15:02; HLA-C03:03; HLA-A68:02	0.30	Yes	No	No	48.4	−61.8
FLLVTLAIL	26	1.42	HLA-C03:03; HLA-A02:01; HLA-B15:02; HLA-C14:02; HLA-A02:06	0.17	Yes	No	No	48.4	−57.2
LLFLAFVVF	18	1.25	HLA-B15:01; HLA-A32:01; HLA-C12:03; HLA-C14:02; HLA-B15:02; HLA-C03:03	0.23	Yes	No	No	32.5	−43.31
VLLFLAFVV	17	1.12	HLA-A02:01; HLA-A02:06; HLA-C12:03; HLA-C14:02	0.26	Yes	No	No	48.4	−80.3
SVLLFLAFV	16	1.05	HLA-A02:06; HLA-C12:03; HLA-A02:01; HLA-A68:02	0.19	Yes	No	No	32.5	−60.31