Research Article
Single Nucleotide Polymorphisms in IFN-γ Signaling Pathway Associated with Risk of Hepatitis B Virus Infection in Chinese Children
Table 1
Basic information of the selected SNP loci in this study.
| SNP | Chr | Chr. position | Alleles | Gene | SNP property | MAF (HapMap-HCB) | MAF (present study) |
| rs3212227 | 5 | 159315942 | G/T | IL12B | 3′-UTR | 0.430 | 0.468 | rs3799488 | 6 | 137198643 | C/T | IFNGR1 | Intron variant | 0.190 | 0.290 | rs2234711 | 6 | 137219383 | A/G | IFNGR1 | 5′-UTR | 0.500 | 0.388 | rs1861494 | 12 | 68157629 | T/C | IFNG | Intron variant | 0.333 | 0.326 | rs1059293 | 21 | 33437386 | C/T | IFNGR2 | 3′-UTR | 0.128 | 0.126 |
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