NDM-1-Positive K. pneumoniae at a Teaching Hospital in Southwestern China: Clinical Characteristics, Antimicrobial Resistance, Molecular Characterization, Biofilm Assay, and Virulence

Table 1

Clinical characteristics of patients with NDM-1-positive K. pneumoniae.

Isolate no.	Gender	Age (yr)	Date of specimen collection	Days in the hospital	Isolation site(s)	Ward	Invasive treatment	Treatment	Outcome
K-N1	Male	45	2017/1/9	89	Sputum	Transplant center	Laparotomy	SCF, MEM, TEC	Recovered
K-N2	Female	Newborn	2017/5/17	39	Sputum	NICU	Umbilical vein cannula	AMC, SCF, FLUCZ, AZT, CRO	Recovered
K-N3	Male	72	2017/6/26	36	Sputum	Elderly general	Tracheal intubation	MEM, KETOC, VA	Died
K-N4	Male	Newborn	2017/9/22	46	Catheter tip	NICU	Umbilical vein intubation; central venous catheterization	SCF, AZT, FLUCZ, TZP, CAZ	Recovered
K-N5	Male	Newborn	2017/12/21	84	Sputum	NICU	Noninvasive ventilator	MEM, AMC, PIS	Recovered
K-N6	Female	Newborn	2018/1/3	10	Sputum	NICU	Tracheal intubation; umbilical vein catheter	AMC, SCF	Died
K-N7	Male	Newborn	2018/1/5	28	Urine	NICU	Umbilical vein catheterization; ventilator oxygen	AMC, FLUCZ	Recovered
K-N8	Male	97	2018/1/10	13	Sputum	Respiratory unit	No	MEM, KETOC, LEV	Recovered
K-N9	Male	90	2018/1/11	20	Sputum	General surgery	No	MEM, FLUCZ	Died
K-N10	Female	Newborn	2018/1/24	20	Urine	NICU	Tracheal intubation; umbilical vein catheterization	MEM, AMC, SCF	Recovered
K-N11	Male	Newborn	2018/2/5	33	Catheter tip	NICU	Tracheal intubation; umbilical vein catheterization	MEM, AMC	Recovered
K-N12	Female	Newborn	2018/2/8	100	Sputum	NICU	Tracheal intubation; umbilical vein catheterization	AMC	Died
K-N13	Male	Newborn	2018/2/12	16	Sputum	NICU	Tracheal intubation	SCF	Recovered
K-N14	Female	Newborn	2018/3/1	51	Urine	NICU	Umbilical vein catheterization; noninvasive ventilator	MEM, AMC, SCF	Recovered
K-N15	Male	85	2018/3/13	27	Sputum	General surgery	No	MOX	Recovered
K-N16	Female	Newborn	2018/5/10	64	Catheter tip	NICU	Tracheal intubation; umbilical vein catheterization	MEM, SCF, IPM	Recovered
K-N17	Male	86	2018/7/27	14	Sputum	Gastroenterology	No	MEM	Died
K-N18	Female	87	2018/7/31	9	Sputum	NICU	No	SCF	Recovered
K-N19	Male	87	2018/8/8	14	Sputum	Respiratory unit	Noninvasive ventilator	MEM, FLUCZ, SCF	Died
K-N20	Male	56	2018/8/29	14	Blood	Neurosurgery	Tracheal intubation, noninvasive ventilator;	MEM, VA	Recovered
K-N21	Male	9	2018/9/28	91	Blood	Neurosurgery	Craniopharyngioma resection; lateral ventricle puncture	MEM, CZO, VA	Recovered
K-N22	Female	49	2020/1/9	56	Blood	ICU	Tracheal intubation	TZP, IMP	Recovered
K-N23	Male	82	2020/2/13	18	Sputum	NICU	Tracheal intubation	CMZ, TZP, IMP	Recovered
K-N24	Female	47	2020/2/28	13	Urine	ICU	Tracheal intubation	LVX, IMP, SCF, MEM	Recovered
K-N25	Male	91	2020/3/9	18	Sputum	Neurosurgery	No	IMP, Cefoselis, LVX	Recovered
K-N26	Male	88	2020/3/12	15	Sputum	Neurosurgery	Tracheal intubation	MEM, TZP, LVX	Recovered
K-N27	Male	62	2020/3/14	25	Urine	ICU	Tracheal intubation	MEM, TZP	Recovered
K-N28	Female	59	2020/3/27	14	Sputum	Neurosurgery	Lateral ventricle puncture	TZP, MXF	Recovered
K-N29	Female	93	2020/4/12	46	Wound	ICU	Tracheal intubation	MEM, TZP, SCF, LVX	Recovered
K-N30	Male	14	2020/4/29	21	Sputum	Hematology	Tracheal intubation	MEM, TZP	Recovered

Notes. SCF: cefoperazone sulbactam; TEC: teicoplanin; MEM: meropenem; CRO: ceftriaxone; MOX: Lafaxed; AMC: amoxicillin clavulanate potassium; KETOC: voriconazole; FLUCZ: fluconazole; AZT: aztreonam; VA: vancomycin; CAZ: ceftazidime.