Potential Predictors of Poor Prognosis among Severe COVID-19 Patients: A Single-Center Study
Table 4
Summary of the Cox regression model for the results of a multivariate analysis of demographics, clinical data, laboratory test, and survival time of severe COVID-19 patients in ICU.
Factors
value
Hazard ratio
95% CI
Age (years) 20–39
0.04
2.73
1.046–7.195
40–59
0.024
2.532
1.133–5.657
60–79
<0.001
4.447
1.948–10.153
≥ 80
—
—
—
Sex (female)
0.005
2.355
1.301–4.264
Diabetes (yes)
0.005
2.178
1.263–3.757
AST (increased)
<0.001
4.346
2.088–9.044
Bilirubin nonconjugated (increased)
0.327
1.484
0.674–3.267
Creatinine (increased)
0.007
6.501
1.677–25.194
BUN (increased)
0.447
1.763
0.369–8.427
Neutrophils (increased)
0.634
1.302
0.401–4.480
Eosinophils (decreased)
0.017
2.211
1.155–4.234
Basophils (decreased)
0.368
1.426
0.658–3.093
Monocytes (decreased)
0.343
1.302
0.755–2.245
Lymphocytes (decreased)
0.894
1.124
0.202–6.244
Symbol “—” indicates unmeasurable values due to linearity issues in the original data. AST: aspartate aminotransferase; BUN: blood urea nitrogen.
