Research Article
Clinical Analysis of Bloodstream Infection of Escherichia coli in Patients with Pancreatic Cancer from 2011 to 2019
Table 3
Analysis of risk factors for E. coli BSI in patients with pancreatic cancer.
| Risk factor | Category | Infected group (n = 31) | Control group (n = 93) | p value | Number of cases | Composition ratio (%) | Number of cases | Composition ratio (%) |
| Gender | Male | 18 | 58.1 | 51 | 54.8 | 0.836 | Female | 13 | 41.9 | 42 | 45.2 |
| Age (years) | ≥60 | 15 | 48.3 | 56 | 60.2 | 0.297 | <60 | 16 | 51.7 | 37 | 39.8 |
| Hospitalization days | ≥7 | 17 | 54.8 | 11 | 11.8 | <0.001 | <7 | 14 | 45.2 | 82 | 88.2 |
| Clinical stage | Late | 27 | 87.1 | 74 | 79.6 | 0.432 | Early | 4 | 12.9 | 19 | 20.4 |
| Number of admissions (times) | ≥2 | 30 | 96.8 | 79 | 84.9 | 0.067 | <2 | 1 | 3.2 | 14 | 15.1 |
| Surgery | Yes | 18 | 58.1 | 6 | 6.5 | <0.001 | No | 13 | 41.9 | 87 | 93.5 |
| Intraoperative bleeding | Yes | 6 | 19.4 | 22 | 23.7 | 0.805 | No | 25 | 80.6 | 71 | 76.3 |
| Chemotherapy | Yes | 21 | 67.7 | 46 | 49.5 | 0.097 | No | 10 | 32.3 | 47 | 50.5 |
| Radiotherapy | Yes | 1 | 3.3 | 0 | 0.0 | 0.250 | No | 30 | 96.7 | 93 | 100.0 |
| Type of antibiotics used (species) | ≥2 | 9 | 29.0 | 12 | 12.9 | 0.052 | <2 | 22 | 71.0 | 81 | 87.1 |
| Distant organ metastasis of cancer | Yes | 16 | 51.6 | 35 | 37.6 | 0.208 | No | 15 | 48.4 | 58 | 62.4 |
| Central venous catheter | Yes | 1 | 3.3 | 0 | 0.0 | 0.250 | No | 30 | 96.7 | 93 | 100.0 |
| Drainage tube | Yes | 12 | 38.7 | 32 | 34.4 | 0.670 | No | 19 | 61.3 | 61 | 65.6 |
| Merger with other parts of infection | Yes | 6 | 19.4 | 16 | 17.2 | 0.790 | No | 25 | 80.6 | 77 | 82.8 |
| Stayed in ICU | Yes | 5 | 16.1 | 8 | 8.6 | 0.308 | No | 26 | 83.9 | 85 | 91.4 |
| Blood transfusion | Yes | 5 | 16.1 | 18 | 19.4 | 0.795 | No | 26 | 83.9 | 75 | 80.6 |
| Combined with diabetes | Yes | 5 | 16.1 | 25 | 26.9 | 0.333 | No | 26 | 83.9 | 68 | 73.1 |
| Glutamine transfusion | Yes | 9 | 29.0 | 37 | 39.8 | 0.391 | No | 22 | 71.0 | 56 | 60.2 |
| White blood cells (/L) | <3.5 × 109 | 2 | 6.5 | 9 | 9.7 | 0.729 | ≥3.5 × 109 | 29 | 93.5 | 84 | 90.3 |
| Neutropenia | Yes | 1 | 3.2 | 4 | 4.3 | 1.000 | No | 30 | 96.8 | 89 | 95.7 |
| Albumin (g/L) | <40.0 | 24 | 77.4 | 48 | 51.6 | 0.012 | ≥40.0 | 7 | 22.6 | 45 | 48.4 |
| Prealbumin (g/L) | <0.2 | 28 | 90.3 | 65 | 69.9 | 0.030 | ≥0.2 | 3 | 9.7 | 28 | 30.1 |
| Death | Yes | 13 | 41.9 | 8 | 8.6 | <0.001 | No | 18 | 58.1 | 85 | 91.4 |
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