Research Article
Antifungal Strategy in Patients with Invasive Fungal Disease Associated with Hematological Malignancies Based on Risk Stratification
Table 2
Patients’ characteristics.
| Baseline data | | Empirical therapy group | Diagnostic-driven therapy group | value |
| Sex | Male | 143 | 142 | 0.27 | Female | 96 | 77 |
| Age | | 49 (39, 60) | 53 (39, 64) | 0.10 |
| Neutropenia duration | | 12.38 ± 10.17 | 10.35 ± 10.67 | 0.04 |
| HMs | AML | 131 | 102 | 0.29 | ALL | 33 | 28 | HAL | 1 | 1 | MDS | 13 | 16 | MM | 10 | 22 | NHL/HD | 47 | 44 | CML | 1 | 2 | CLL | 3 | 4 |
| Disease status | Newly diagnosed | 110 | 100 | 0.75 | CR | 23 | 20 | Relapsed/refractory | 54 | 43 | PR/SD | 52 | 56 |
| Glucocorticoids for more than 3 weeks | Yes | 47 | 44 | 0.91 | No | 192 | 175 |
| IFD history | Yes | 56 | 45 | 0.46 | No | 183 | 174 |
| Diabetes | Yes | 22 | 33 | 0.07 | No | 217 | 186 |
| Pulmonary dysfunction | Yes | 3 | 6 | 0.25 | No | 236 | 213 |
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