Antifungal Strategy in Patients with Invasive Fungal Disease Associated with Hematological Malignancies Based on Risk Stratification

Table 6

Risk factors for IFD based on univariate analysis.

Factors		Proven/probable IFD	Possible/undefined IFD	χ^2	value
Age	≥65	10	82	0.141	0.707
	<65	45	321
Sex	Male	35	250	0.053	0.818
	Female	20	153
Primary disease	Acute leukemia	43	253	5.022	0.025
	Nonacute leukemia	12	150
Disease status	Recurrence/relapse	18	77	8.696	0.013
	Newly diagnosed	27	183
	CR/PR/SD	10	143
Neutropenia duration	<7 d	12	153	10.109	0.006
	≥7 d and <14 d	12	110
	≥14 d	31	140
IFD history	Yes	21	80	9.46	0.002
	No	34	323
Glucocorticoids for more than 3 weeks	Yes	16	75	3.339	0.068
	No	39	328
Diabetes	Yes	14	41	10.694	0.001
	No	41	362
Pulmonary dysfunction	Yes	6	8	13.006	0.193
	No	49	395
Hypoproteinemia	Yes	45	311	0.604	0.437
	No	10	92
Deep vein catheterization	Yes	36	351	0.771	0.38
	No	9	62