Research Article
The Investigation of HBV Pre-S/S Gene Mutations in Occult HBV Infected Blood Donors with anti-HBs Positive
Table 2
The amino acids substitutions of envelope protein in OBI strains compared with wild-type HBV strains.
| | Region | Mutation frequency/strains | Mutation frequency/strains | P value | | (Mutation rate in OBI strains) | (Mutation rate in wt-HBV strains) | (OBI vs. wt-HBV) |
| | OBIB | | pre-S1 | 5/4 (1.05%) | 22/15 (1.23%) | 1.000 | | pre-S2 | 7/4 (1.47%) | 12/15 (0.67%) | 0.095 | | S | 52/10 (3.6%) | 24/15 (1.11%) | <0.001 |
| | OBIC | | pre-S1 | 28/7 (3.36%) | 22/15 (1.23%) | 0.001 | | pre-S2 | 17/7 (2.04%) | 9/15 (0.60%) | <0.001 | | S | 79/11 (4.99%) | 12/15 (0.56%) | <0.001 |
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OBIB, OBI genotype B; OBIC, OBI genotype C; wt-HBV, wild-type HBV.
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