Review Article

Stroke in Patients with Schistosomiasis: Review of Cases in Literature

Table 3

Clinical presentation, cerebrovascular involvement, laboratory investigation results, additional events, neurological and overall outcome details in patients with stroke and schistosomiasis.

Clinical presentation
 Eosinophilia was the most frequent finding, followed by cardiac abnormalities (myocarditis/ST wave inversion), disorientation and confusion, fever, gait ataxia, hemiplegia, headache, urticaria, memory impairment, dysarthria and other non-specified speech disturbance.

Cerebrovascular involvement
 Watershed infarction, cerebral vasculitis, vasculitis and stenosis of the extracranial portion of the carotid artery have been described in different patients affected by schistosomiasis reported.

Laboratory investigations
 On admission patient have presented with positive serology or seroconversion occurred during hospitalization. In some cases were stool and urinary samples were negative on admission, a late stool and urine positivity has be observed.

Additional events
 Case 5: VI nerve palsy deemed to be caused by worsening of the vasculitis at the right carotid syphon level, with consequent compression of the nerve trunk [6].
 Case 8: new cerebral infarcts, detected at MRI, 9 weeks after the first event [16].

Neurological outcome
 Case 1: no recurrence of neurological symptoms was reported, but details of outcome were not provided.
 Cases 2, 4, 7: A full neurological recovery was reported respectively after 6 months, 48 h and 5 days after steroid therapy.
 Case 3: psychomotor impairment and insomnia persisted at 4 months.
 Case 5: no information on clinical improvement was reported. Diplopia due to VI nerve palsy regressed 24 hours after steroid therapy, with no relapse. Minor improvement of carotid stenosis was reported at 6 month follow-up [6].
 Case 6: no specified outcome
 Case 8: partial recovery of gait occurred, which became possible without aid.

Overall outcome
 No deaths have been reported among cases