Association of Antibiotic Resistance Traits in Uropathogenic Escherichia coli (UPEC) Isolates
Table 5
Comparative association of antimicrobial resistance in uropathogenic E. coli isolates according to phenotypic and genotypic results.
Antimicrobial agents
Characteristics of isolate
Agreement between phenotypic and genotypic resistance¶ (n = 42)
NP
ARGs
NG
P+/G-
P-/G+§
OR
95% CI
κ
Ampicillin
22
CITM
5
18
1
4.22
0.43–41.45
0.216
0.13
22
blaSHV
11
11
0
41
2.20–761.79
0.012
0.49
Gentamicin
11
aac(3)-IV
2
10
1
3.00
0.17–52.53
0.451
0.08
Streptomycin
12
aadA1
3
10
1
5.8
0.47–71.07
0.169
0.17
Ciprofloxacin
7
qnrA
5
3
1
45.33
3.76–546.25
0.002
0.61
Tetracycline
39
tet(A)
33
8
2
1.94
0.16–24.16
0.607
0.07
tet(B)
32
9
2
1.67
0.13–20.58
0.690
0.05
Chloramphenicol
12
catA1
5
8
1
14.5
1.42–148.57
0.024
0.36
cmlA
8
6
2
14
2.25–87.02
0.004
0.48
Trimethoprim-sulphamethaxole
20
dfrA1
15
6
1
49
5.31–452.24
<0.001
0.66
Sulfonamide
30
sul1
26
5
1
55
5.73–527.66
<0.001
0.68
Erythromycin
12
ere(A)
3
10
1
5.8
0.47–71.07
0.169
0.17
NP, number of E. coli expressing phenotypic resistance to the indicated antimicrobial agent. NG, number of E. coli carrying the indicated antimicrobial resistance gene. P+/G-, number of phenotypically resistant E. coli (P+) with no resistance gene (G-) for the drug tested. §P-/G+, number of phenotypically susceptible E. coli (P-) with a resistance gene (G+) for the drug tested. ¶Association between AMR phenotypes and ARGs and phenotype-genotype intertest agreement. n, number of E. coli.
