Research Article

Biomarkers of Inflammation among Patients with COVID-19: A Single-Centre Prospective Study from Prishtina, Kosovo

Table 4

Distribution of biochemical and hematological parameters across disease severity groups.

MildModerateSevereCritical value

CRP (mg/L)n (Mean rank)8 (11.69)23 (28.48)50 (53.67)4 (55.75)≤0.001
D-dimer (ng/ml)n (Mean rank)8 (30.56)20 (33.73)48 (43.49)4 (58.38)0.097
LDH (U/L)n (Mean rank)0 (0.00)16 (17.06)33 (30.85)4 (35.00)0.008
CK (U/L)n (Mean rank)0 (0.00)11 (17.91)30 (23.32)3 (31.17)0.235
ESR (mm/h)n (Mean rank)4 (9.75)21 (26.76)38 (39.12)4 (47.63)0.003
WBC (×109/L)n (Mean rank)8 (14.25)22 (40.00)50 (47.74)4 (47.25)0.004
Granulocytes (%)n (Mean rank)8 (12.13)19 (25.24)43 (46.90)4 (45.50)≤0.001
Lymphocytes (%)n (Mean rank)8 (62.19)20 (50.58)44 (29.41)4 (30.75)≤0.001
Monocytes (%)n (Mean rank)8 (50.44)18 (39.08)33 (24.91)4 (21.75)0.001
Platelet countn (Mean rank)8 (33.75)22 (43.07)49 (45.40)4 (11.00)0.036

values less than 0.05 are highlighted in italics. Statistical analyses were performed with the Kruskal–Wallis test. IL-6, interleukin 6; CRP, C‐reactive protein; LDH, lactate dehydrogenase; CK, creatine kinase, ESR, erythrocyte sedimentation rate; WBC, white blood cells.