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Author/ Year/country | Age/gender | Comorbidities | Name of vaccine | Time interval/dose | Vaccine side effects | MG first signs and symptoms | Physical examination findings | Laboratory findings | EMG findings | Radiologic findings | Acute treatment | Main treatment | Final outcome |
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Augustine Chavez et al./August 2021/USA [18] | 82/M | Laryngeal cancer (hemi-laryngectomy) and barrett’s esophagus, stage 3 CKD | BNT162b2 | 2 days/2nd | NR | Slurred speech, perioral numbness, and difficulty in chewing and spitting | Hoarse voice, normal neurologic examination (healthy cranial nerve, no cognitive, sensory, or motor deficits) | AchR-binding antibody titer: 11.4, AchR modulating antibody: 93%, and Striational antibody titer: 1 : 245760 | RNST: decrement response | Head CT scan: changes in white matter (as a result of aging), and no acute intracranial abnormality, MRI: no laryngeal tumor | NR | Pyridostigmin, speech therapy, steroids, and IVIG | Discharged (transferred to a rehabilitation center) |
Myung Ah Lee et al./November 2021/Korea [14] | 33/F | No medical history | BNT162b2 | The evening of the injection/ 2nd | Myalgia | Generalized weakness, binocular diplopia, bilateral ptosis, difficulty with moving her arms and neck, dysarthria, and dysphagia | Both lower and upper extremities MRC scale: 4.5, sensory and motor NCS results: normal | AchR antibody titer: <0.02 nmol/L and Neostigmine test confirmed the diagnosis of MG | RNST: remarkable decrement response of right orbicularis oculi | Chest CT: mild thymus hyperplasia | NR | Oral pyridostigmine (360 mg/day) | Recovered and discharged |
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Abdulla Watad et al./March 2021/Israel [17] | 72/M | Recurrent pericarditis (colchicine-treated) | BNT162b2 | 1 day/2nd | NR | NR | NR | NR | Decrement response on the shoulder and facial muscles (28 to 46%) | NR | PLEX | Prednisone 60 mg | Recovered |
73/M | NR | BNT162b2 | 7 days/2nd | NR | Started with ocular signs continued with respiratory symptoms and bulbar signs | NR | NR | Borderline decrement but remarkable pathologic jitter | NR | PLEX | Pyridostigmin, prednisone | Intubated |
Giuliana Galassi et al./January 2022/Italy [19] | 73/M | Mild hypertension and myocardial infarction (smoker) | ChAdOx1 | 8 days/1st | Myalgia and Fever (up to 39°C) | Psoriasis (in both elbows) and Painless left-sided ptosis | NR | RF: 240 IU/ml, COVID-19 PCR: Negative, Anti- AChR antibody titer: 1.9 nmol/l | RNST: Decrement response in nasalis muscle (14.7%) and Normal response in the ulnar and accessory nerves | Brain CT: normal Chest CT: No thymoma | Paracetamol | Pyridostigmine bromide (240 mg per day) | Recovered |
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