Research Article

Investigating Antimicrobial Resistance and ESBL Producing Gene in Klebsiella Isolates among Neonates and Adolescents in Southern Bangladesh

Table 1

Clinical characteristics of Kpn infected patients (n = 501).

VariablesResistant to one/two antibioticMultidrug-resistantTotal cases (n = 501)Pearson’s c2-value

Gender
Male36 (14.87%)189 (78.099%)242 (48.303%)104.04<0.001
Female75 (28.95%)167 (64.478%)259 (51.696%)34.975

Age Groups
Baby/Newborn (0–4 weeks)45 (20.93%)143 (66.51%)215 (42.91%)51.085<0.001
Baby/Infant (4 week–<1 year)18 (22.22%)58 (71.604%)81 (16.167%)21.053
Toddler (1– <3 years)8 (11.59%)58 (84.057%)69 (13.77%)37.879
Preschooler (3– <5 years)11 (39.285%)17 (60.71%)28 (5.588%)1.2857
Childhood (5– <12 years)15 (23.809%)46 (73.015%)63 (12.57%)15
Adolescent (12–18 years)8 (17.77%)33 (73.33%)45 (8.98%)15.244

Patient Type
Indoor/Ward51 (19.615%)193 (74.23%)260 (51.896%)82.639
Outdoor60 (24.89%)163 (67.634%)241 (48.104%)47.574

Sample Types
Urine49 (26.486%)125 (67.567%)185 (36.92%)33.195<0.001
Tracheal aspirates13 (13.54%)81 (84.375%)96 (19.16%)49.191
Pus17 (28.33%)41 (68.33%)60 (11.976%)9.931
Blood9 (10.227%)70 (79.545%)88 (17.56%)47.101
Sputum10 (37.037%)11 (40.740%)27 (5.389%)0.047619
Wound swab6 (35.294%)17 (68%)25 (4.99%)5.2609
HVS7 (58.33%)5 (41.6666%)12 (2.395%)0.33333
Throat swab0 (0.00%)5 (83.33%)6 (1.197%)5
Umbilical swab0 (0.00%)2 (100%)2 (0.399%)2

Regional Distribution
Urban1371783150.690.4
Rural73113186

Correlation analysis between single drug and multidrug-resistance among different groups of Kpn isolates. indicates statistically significant ( value is less than 0.05).