Assessment of Intravenous Antibiotics to Peroral Antibiotics Conversion Practice and Its Associated Factor at University of Gondar Comprehensive Specialized Hospital: Prospective Observational Study
Table 3
Logistic regression analysis of antibiotics conversion practice at UOGCSH (n = 324).
Variable
Category
Not converted to PO
COR (95%CI)
value
AOR (95%CI)
value
Yes
No
Physician experience
Specialist
5
11
1
1
Intern
121
62
4.3 (1.43 –12.9)
0.009
3.91 (.92–16)
0.064
GP
58
41
3.11 (1.005–9.64)
0.049
1.82 (0.41–8.1)
0.43
Resident
9
17
1.16 (0.3–4.4)
0.82
0.31 (0.046–2.1)
0.23
Febrile
No
46
68
1
1
Yes
147
63
3.45 (2.14–5.55)
0.0001
1.43 (1.33–3.23)
0.034
Tachypenia
No
67
98
1
1
Yes
126
33
5.58 (3.4–9.14)
0.03
1.89 (1.9–5)
0.0001
Hypotention
No
54
78
1
1
Yes
139
53
3.8 (2.4–6)
0.0001
2.55 (0.13–5.7)
0.42
Tachycardia
No
58
56
1
1
Yes
135
75
1.73 (1.09–2.76)
0.019
1.7 (0.76–3.7)
0.189
Availability of medication
Available
139
80
1
1
Not available
54
51
1.64 (1.024–2.63)
0.039
3.27 (1.42–7.53)
0.005
Leucocytosis
No
107
113
1
1
Yes
86
18
5.045 (2.84–8.94)
0.006
3.36 (0.34–8.4)
0.53
Length of hospital stay (mean ± SD)
≤10.78 ± 6.6
73
115
1
1
>10.78 ± 6.6
120
16
11.8 (6.5–21.5)
0.01
1.82 (1.7–4.7)
0.039
Comorbidity
No
107
113
1
1
Yes
94
10
9.93 (10.5–14.8)
0.0002
2.74 (1.9–7.6)
0.026
∗Significance (). Abbreviation: SD: standard deviation; GP: general practitioner.