Review Article

IVIG plus Glucocorticoids versus IVIG Alone in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19: A Systematic Review and Meta-Analysis

Table 1

Baseline characteristics of the included studies.

StudyYearNo. of patientsInterventionNo. of patientsAgeMale sex (%)Outcomes

Ouldali et. al.202198IVIG + GC329.1 (4.7–13.1)53Treatment failure, adjunctive therapy, inotropic support, LV dysfunction, and duration of PICU stay
IVIG648.7 (4.6–12)48
McArdle et. al.2021454IVIG + GC2088.8 (4.6–12)61Ventilated or death, improvement, treatment escalation, fever, death, any deterioration, LV dysfunction, and aneurysm
IVIG2467.0 (3.7–11)64
Son et. al.2021206IVIG + GC1038.8 (3.6–12)56Cardiovascular dysfunction, LV dysfunction, inotrope use, adjunctive therapy, and persistence of fever
IVIG1037.6 (5.4–12.6)57