IVIG plus Glucocorticoids versus IVIG Alone in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19: A Systematic Review and Meta-Analysis
Table 1
Baseline characteristics of the included studies.
Study
Year
No. of patients
Intervention
No. of patients
Age
Male sex (%)
Outcomes
Ouldali et. al.
2021
98
IVIG + GC
32
9.1 (4.7–13.1)
53
Treatment failure, adjunctive therapy, inotropic support, LV dysfunction, and duration of PICU stay
IVIG
64
8.7 (4.6–12)
48
McArdle et. al.
2021
454
IVIG + GC
208
8.8 (4.6–12)
61
Ventilated or death, improvement, treatment escalation, fever, death, any deterioration, LV dysfunction, and aneurysm
IVIG
246
7.0 (3.7–11)
64
Son et. al.
2021
206
IVIG + GC
103
8.8 (3.6–12)
56
Cardiovascular dysfunction, LV dysfunction, inotrope use, adjunctive therapy, and persistence of fever