Differential Infectivity of Human Neural Cell Lines by a Dengue Virus Serotype-3 Genotype-III with a Distinct Nonstructural Protein 2A (NS2A) Amino Acid Substitution Isolated from the Cerebrospinal Fluid of a Dengue Encephalitis Patient

Figure 3

DENV-3 RNA genome levels as determined from infected cells at 0, 24, 48, 72, 96, and 120 h postinfection determined by RT-qPCR at a multiplicity of infection (MOI) of 0.01 and 0.001. DENV-3 isolated from the cerebrospinal fluid (CSF) specimen (CSF-11098) and the serum specimen (HP-5528) was separately inoculated to C6/36, SKNSH, T98G, and N2A cell lines. P value was determined by the t-test. P value 0.05 was considered significant.