Evaluation of the Efficacy and Safety of Intravenous Immunoglobulin (IVIG) in Moderate-to-Severe Hospitalized COVID-19 Patients: A Randomized, Open-Label Parallel-Group Study

Table 4

The vital parameter-related outcome, CTSS, and NEWS2.

Parameters	IVIG + SoC (mean ± SD) Day 1	IVIG + SoC (Day 9)	value	Standard of care (SoC) (Day 1)	Standard of care (SoC) (Day 9)	value
Number	33			26
Systolic BP (mm Hg)	128.52 ± 17.21	123.46 ± 12.15	0.1725	128.88 ± 17.05	123.38 ± 14.69	0.206
Diastolic BP (mm Hg)	78.52 ± 10.37	78.54 ± 10.10	0.8331	77.00 ± 9.31	75.69 ± 12.46	0.519
Pulse rate	93.42 ± 10.47	91.57 ± 9.86	0.5027	103.12 ± 16.43	96.65 ± 16.97	0.228
Respiratory rate	25.33 ± 3.89	19.86 ± 3.77	<0.0001	24.92 ± 2.06	24.70 ± 3.06	0.982
SPO2 (on O2 support)	94.48 ± 3.79	96.04 ± 2.78	0.0611	91.65 ± 3.25	93.35 ± 2.64	0.043
Random blood sugar (mg/dL)	252.69 ± 97.43	279.57 ± 125.37	0.6144	270.64 ± 99.69	287.19 ± 153.30	0.701
CTSS
Mean	21.67	17.97	<0.0001	21.23	20.69	0.5754
SD	2.25	3.77		2.90	3.93
NEWS2
Mean	6.67	5.67	0.0277	6.92	5.96	0.0019
SD	1.08	2.31		1.13	0.97

Bold values denote significant P-values (≤0.05).