Research Article

Campylobacter jejuni Modulates Reactive Oxygen Species Production and NADPH Oxidase 1 Expression in Human Intestinal Epithelial Cells

Figure 3

Proposed structure of the NOX1 complex consisting of NOX1, p22phox, GTP-bound Rac1, NOXA1, and NOXO1. p22phox and other subcellular subunits are assembled to activate catalytic subunit NOX1 which results in the generation of O2āˆ’ by oxidising NADPH [17]. Created with http://BioRender.com.