Mucus Distribution Model in a Lung with Cystic Fibrosis
Figure 1
Image data (a, c) and corresponding lung density maps (b, d) for a healthy male (41 yo, FEV1[pred] (a, b)) and a CF male with severe disease ( yo, FEV1[pred] (c, d)) using an MRI methodology as described in a study conducted by Theilmann et al. [6]. The artifact in the chest wall in (d) is due to a metal ring in an installed port-a-cath. The hyperintense regions in the lung density map of the CF subject (d) indicate lung regions full of mucus and regions showing an absence of water are associated with tissue scarring. Neither observation is seen in the healthy subject.
