ModeLang: A New Approach for Experts-Friendly Viral Infections Modeling

Algorithm 3

0 < 𝑠 < 4

0.002 < rHU < 3.4

0 < rHI < 1.4𝑒--6

1𝑒--3 < dHU < 0.014

1𝑒--3 < dHI < 0.5

4𝑒6 < Umax < 1.3𝑒7

1𝑒--8 < beta < 1𝑒--6

0.1 < pH < 44

0.8 < cv < 22

0 < cI < 1

Healthy hepatocytes are created by

  Healthy hepatocytes at speed rHU

Infected hepatocytes are created by

  Infected hepatocytes at speed rHI

The number of Healthy hepatocytes and

  Infected hepatocytes is less than Umax

Blastic cells change into

  Healthy hepatocytes at speed 𝑠

Healthy hepatocytes die with mean time dHU

Infected hepatocytes die with mean time dHI

Healthy hepatocytes and Virions generate

   Infected hepatocytes with probability

   beta

Virions are emitted by Infected hepatocytes

  at rate pH

Virions die with probability cv

Infected hepatocytes change into

  Healthy hepatocytes with probability cI