Nanodosimetry-Based Plan Optimization for Particle Therapy

Figure 4

Composite ICSDs obtained in the five target voxels (2–6) and in the two normal tissue voxels (1 and 7) for the single-field proton plan with unit PB fluence. Left panel: absolute distributions. Due to the the large frequency of zero clusters, the zero bin is not shown for a better visualization of the plot. Right panel: conditional distributions. In the legend box, the left panel shows the coding of the corresponding voxels (refer to Figure 1 for the voxel numbering scheme). The legend box in the right panel also shows the for each voxel.

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