Computational Insight into Protein Tyrosine Phosphatase 1B Inhibition: A Case Study of the Combined Ligand- and Structure-Based Approach

Figure 8

Docking of compounds 3 (a), 5 (b), 7 (c), 8 (d), 12 (e), and 16 (f) into the active site of PTP1B with key amino acid residues (colored by green) in represented ligand binding poses. The pictures were prepared by PyMol software.

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(b)

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