Computational Insight into Protein Tyrosine Phosphatase 1B Inhibition: A Case Study of the Combined Ligand- and Structure-Based Approach

Table 1

Activities of the selected compounds.

Compound	IC50 (nM)	(nM)	Ref.
1	210		[16]
2	185		[16]
3	65		[16]
4	110		[21]
5	330		[21]
6	31		[21]
7	7		[17]
8	90		[17]
9		36	[18]
10		4	[18]
11		13	[22]
12		740	[22]
13		310	[18]
14		21	[22]
15		22	[22]
16		0.68	[18]