Stimulation Strategies for Tinnitus Suppression in a Neuron Model

<div>Inactivation IA versus patch area for<i> I</i><sub>0</sub>=6 <i>μ</i>A/cm<sup>2</sup> (purple lines),<i> I</i><sub>0</sub>=7 <i>μ</i>A/cm<sup>2</sup> (green lines), and<i> I</i><sub>0</sub>=10 <i>μ</i>A/cm<sup>2</sup> (magenta lines), obtained by combining the CW at 25 kHz 10 mV and the GWN, <svg height="9.37076pt" id="M38" style="vertical-align:-3.22717pt" version="1.1" viewbox="-0.0498162 -6.14359 14.2702 9.37076" width="14.2702pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M548 455L523 469C505 448 490 439 461 439C416 439 374 447 316 447C144 447 23 310 23 161C23 47 89 -12 179 -12C312 -12 429 106 429 244C429 303 419 344 368 386L371 388C404 383 440 378 474 378C507 378 530 411 548 455ZM350 274C350 191 308 25 198 25C144 25 108 75 108 157C108 264 170 395 276 395C296 395 320 384 333 360C347 334 350 316 350 274Z" id="g113-240"></path></g><g transform="matrix(.0091,0,0,-0.0091,6.76,3.132)"><path d="M731 650H485V618C556 614 580 601 585 558C588 530 592 485 592 390V153H589L173 650H22V618C69 614 92 606 112 582C131 558 132 555 132 483V266C132 175 129 128 125 96C120 49 95 36 36 33V0H281V33C212 36 188 50 183 98C180 129 177 175 177 266V510H179L603 -9H638V390C638 483 640 530 644 561C649 602 674 615 731 618V650Z" id="g58-76"></path></g></svg>=10 mV (solid lines), compared with the superposition of the inactivations induced by the two stimulations applied individually (dashed lines).</div>

Computational and Mathematical Methods in Medicine

Stimulation Strategies for Tinnitus Suppression in a Neuron Model

Figure 4