Modeling the Spatiotemporal Dynamics of Oncolytic Viruses and Radiotherapy as a Treatment for Cancer

Figure 4

The ratio of the uninfected cancer mass to its initial mass is plotted after day 5 from the beginning of virotherapy alone. The red curve represents radiovirotherapy with three types of radiation delivery: constant, decaying, and periodic delivery, whereas the blue curve means that virotherapy continues without radiotherapy.

(a) Constant radiation

(b) Decaying radiation

(c) Periodic radiation