Network Structure Analysis Identifying Key Genes of Autism and Its Mechanism

Table 2

MD-Gs.

No	Genes	Description	Expression
1	HYI	Hydroxypyruvate isomerase	E > C
2	PPP1R37	Protein phosphatase 1 regulatory subunit 37	E > C
3	HOXD9	Homeobox D9	E > C
4	EXTL1	Exostosin like glycosyltransferase 1	E > C
5	MED13	Mediator complex subunit 13	C > E
6	C7orf63	Cilia and flagella associated protein 69	E > C
7	ARHGDIG	Rho GDP dissociation inhibitor gamma	E > C
8	JUP/KRT17	Junction plakoglobin/type I keratin, acidic	E > C
9	NPY4R	Neuropeptide Y receptor Y4-2	E > C
10	NDRG4	NDRG family member 4	E > C
11	POU3F2	POU class 3 homeobox 2	E > C
12	LOC284788	Uncharacterized LOC284788	E > C
13	USP8	Ubiquitin specific peptidase 8	C > E
14	OGFRP1	Opioid growth factor receptor pseudogene 1	E > C
15	FIGF	Vascular endothelial growth factor D	E > C
16	ZBP1	Insulin like growth factor 2 mRNA binding protein 1	C > E
17	PML	Promyelocytic leukemia	C > E
18	CSF3	Colony stimulating factor 3	E > C
19	FSD1	Fibronectin type III and SPRY domain containing 1	E > C
20	MESP1	Mesoderm posterior bHLH transcription factor 1	E > C

The column of “Expression” shows the comparison of the average expression profiles of key structural genes between C and E.