Network Structure Analysis Identifying Key Genes of Autism and Its Mechanism

Table 3

Top 6 clusters with their representative enriched terms (one per cluster).

No	GO	Description	Count	%	Log 10 (P)	Log 10 (q)	Genes
P1	GO:0048732	Gland development	4	20	−3.40	0.00	HOXD9, PML, POU3F2, MESP1
P2	GO:0051301	Cell division	4	20	−2.88	0.00	FIGF, USP8, FSD1, POU3F2
P3	GO:G0030111	Regulation of Wnt signaling pathway	3	15	−2.79	0.00	JUP, USP8, MESP1
P4	GO:0048562	Embryonic organ morphogenesis	3	15	−2.78	0.00	HOXD9, MESP1, NDRG4
P5	GO:0001568	Blood vessel development	4	20	−2.5	0.00	FIGF, JUP, PML, MESP1
P6	GO:0051090	Regulation of DNA binding transcription factor activity	3	15	−2.29	0.00	CSF3, JUP, CMED13

“Count” is the number of genes in the user-provided lists with membership in the given ontology term. “%” is the percentage of all of the user-provided genes that are found in the given ontology term (only input genes with at least one ontology term annotation are included in the calculation). “Log10 (P)” is the value in log base 10. “Log10 (q)” is the multitest adjusted p value in log base 10. The category of clusters in Table 3 is GO Biological Processes.