Computational Study to Identify the Effects of the KCNJ2 E299V Mutation in Cardiac Pumping Capacity

<div>Electrical activation time (EAT) and electrical deactivation time (EDT) during 600 ms sinus rhythm. WT, wild type; WT/E299V, E299V mutation is moderately expressed heterogeneously; E299V, E299V mutation is purely expressed. (a) Horizontally sliced layers of EAT and EDT (from 30 ms to 510 ms). (b) Minimum and maximum values of EAT and maximum value of EDT.</div>

Computational and Mathematical Methods in Medicine

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Figure 4

Figure 4: Computational Study to Identify the Effects of the KCNJ2 E299V Mutation in Cardiac Pumping Capacity 