Computational Study to Identify the Effects of the KCNJ2 E299V Mutation in Cardiac Pumping Capacity

Table 1

Cardiac mechanical responses during 600 ms BCL of sinus rhythm.

	Stroke volume (mL)	Ejection fraction (%)	Stroke work (mmHg·mL)	ATP consumption rate (s^−1)	SW/ATP	Cardiac output (mL)
WT	59	54	5,771	47	124	5,852
WT/E299V	22	15	712	18	40	2,209
E299V	4	3	16	5	3	378

WT, wild type; WT/E299V, E299V mutation is moderately expressed heterogeneously; E299V, E299V mutation is purely expressed; SW, stroke work; ATP, adenosine triphosphate.