Construction and Evaluation of a Tumor Mutation Burden-Related Prognostic Signature for Thyroid Carcinoma

Figure 1

Statistical analysis on mutational signature of thyroid carcinoma. (a) Waterfall plot of the top 30 mutated genes in each sample. The abscissa represents different samples, and the ordinate represents the top 30 genes. The filled color represents that the gene mutated in the sample, and different colors represent different variant classifications. (b)–(d) According to different classification methods, variant classification, variant types, and SNV class were analyzed. SNV stands for single nucleotide variants. INS stands for insertion. DEL stands for deletion. (e) Histogram indicates the total number of variants per sample of thyroid carcinoma. (f) Box plot shows the distribution of variant classification in cancer samples. (g) Top 10 mutated genes in thyroid carcinoma samples.

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