Construction and Evaluation of a Tumor Mutation Burden-Related Prognostic Signature for Thyroid Carcinoma

Figure 3

DEGs and enrichment analyses. (a) Volcano map of DEGs in high- and low-TMB groups (red dots represent notably upregulated genes; green dots represent notably downregulated genes). (b) Bubble chart of DEGs in GO enrichment analysis. The color of nodes with a small value tends to be red; as the number of genes in the enrichment term increases, the size of nodes also increases. (c) Results of KEGG enrichment analysis of DEGs. The left half circle presents the genes enriched in each signaling pathway. Red represents upregulation, and blue represents downregulation. The color of gene with a larger |logFC| tends to be darker. The right half circle represents the main enriched signaling pathways, and each signal pathway is represented by a different color.

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