Construction and Evaluation of a Tumor Mutation Burden-Related Prognostic Signature for Thyroid Carcinoma

Figure 5

Evaluation of efficacy and independence of the prognostic signature. (a) Survival analysis on the high- and low-risk groups in the training set. (b) Survival analysis on the high- and low-risk groups in the test set. (c) In the training set, ROC curves were plotted based on the prognostic signature. (d) In the test set, ROC curves were plotted based on the prognostic signature. (e) Combined with common clinicopathological features, univariate Cox regression analysis was conducted on risk scores. (f) Combined with common clinicopathological features, multivariate Cox regression analysis was conducted on risk scores. (g) Combined with common clinicopathological features and risk score, a nomogram was plotted to predict 3-year and 5-year survival of patients. (h) and (i) The performance of the nomogram was validated through calibration curves.

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