[Retracted] Porcine-Stimulated Human Tr1 Cells Showed Enhanced Suppression in Xenoantigen Stimulation Response

Figure 3

Tr1 expansion in the presence of the anti-IL-5 antibody and suppressive capacity of expanded XN-1 cells with POM-1. (a) PC-1 and XN-1 cells were counted after 7 days and 14 days of polyclonal or xenoantigen stimulation. Tr1 expansion efficacy was determined as fold expansion as mentioned in Figure 1. (b) XN-1+POM-1, PC-1, and XN-1 cell suppression of responder cell proliferation in xenoantigen-driven stimulated MLR. PC-1: polyclonal Tr1; XN-1+POM-1: Tr1 with xenoantigen specificity in the presence of the CD39 inhibitor POM-1; XN-1: Tr1 with xenoantigen specificity. ; .

(a)

(b)