Research Article

[Retracted] Study on PD-L1 Expression in NSCLC Patients and Related Influencing Factors in the Real World

Table 5

PD-L1 detection techniques for different immunotherapy agents.

DrugMechanismCompanyPD-L1 detection technologyThresholds in clinical studies

AtezolizumabPD-L1RocheVentana PD-L1 (SP142) assayTC0/1/2/3 or IC0/1/2/3
AvelumabPD-L1EMDWithout testing1% or higher
DurvalumabPD-L1AstraZenecaVentana PD-L1 (SP263) assay25% or higher
PembrolizumabPD-1MerckDako PD-L1 IHC 22CS pharmDx1% or 50% or higher
NivolumabPD-1BMSDako PD-L1 IHC 28-8 pharmDx≥1% or ≥5% or ≥10%