Research Article

[Retracted] lncENST Suppress the Warburg Effect Regulating the Tumor Progress by the Nkx2-5/ErbB2 Axis in Hepatocellular Carcinoma

Figure 2

Effect of lncENST on cellular metabolism and tumor growth. The cellular metabolism of LO2 normal liver cells was evaluated by measuring (a) glucose uptake and (b) lactic acid production. The cellular metabolism of liver cancer cells was evaluated by measuring (c) glucose uptake and (d) lactic acid production, which are indicative of the Warburg effect. (e) Tumor growth in HCC-xenografted mice after lnc-INT/OV injection and RFA treatment. (f) Apoptosis of tumor tissues extracted from HCC-xenografted mice after lnc-INT/OV injection and RFA treatment. Positive staining is indicated in brown. Black arrows point to specific areas of positive staining. For (a)–(c), the data are expressed as the , , . For (d), , ×100.
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