Identification of Immune-Related Genes in Sepsis due to Community-Acquired Pneumonia

Table 1

Top 3 enrichment analysis results of functions and pathways of 8 submodules.

MCODE	GO	Description	Log10 ()
MCODE_1	hsa04658	Th1 and Th2 cell differentiation	-31.8
MCODE_1	hsa04659	Th17 cell differentiation	-30.9
MCODE_1	GO:0050852	T cell receptor signaling pathway	-27.2
MCODE_2	GO:0070098	Chemokine-mediated signaling pathway	-15.1
MCODE_2	GO:1990869	Cellular response to chemokine	-14.8
MCODE_2	GO:1990868	Response to chemokine	-14.8
MCODE_3	GO:0007200	Phospholipase C-activating G protein-coupled receptor signaling pathway	-6.6
MCODE_3	hsa04080	Neuroactive ligand-receptor interaction	-5.2
MCODE_4	GO:0042613	MHC class II protein complex	-9.6
MCODE_4	GO:0023026	MHC class II protein complex binding	-9.6
MCODE_4	GO:0023023	MHC protein complex binding	-9
MCODE_5	hsa04144	Endocytosis	-5.9
MCODE_6	GO:0005925	Focal adhesion	-5.3
MCODE_6	GO:0005924	Cell-substrate adherens junction	-5.3
MCODE_6	GO:0030055	Cell-substrate junction	-5.3
MCODE_7	GO:0044772	Mitotic cell cycle phase transition	-4.8
MCODE_7	GO:0051301	Cell division	-4.8
MCODE_7	GO:0044770	Cell cycle phase transition	-4.8
MCODE_8	GO:0098742	Cell-cell adhesion via plasma-membrane adhesion molecules	-5.8
MCODE_8	GO:0030667	Secretory granule membrane	-5.7
MCODE_8	GO:0043312	Neutrophil degranulation	-5.1