[Retracted] The N6-Methyladenosine- (m6A-) Associated Genes Act as Strong Key Biomarkers for the Prognosis of Pancreatic Adenocarcinoma

Table 1

m6A methylation-related genes.

Official symbol	Function
METTL3	Catalyzes m6A modification
METTL14	Balances the assembly of MTC and demonstrates detailed RNA sequence
METTL16	Catalyzes m6A modification
YTHDC1	Promotes RNA splicing and export
YTHDC2	Improves the protein synthetic activation of target mRNA while reduces the profusion of target mRNA
YTHDF1	Promotes mRNA translation
YTHDF2	Promotes mRNA degradation
YTHDF3	Interacts with YTHDF1 to promote mRNA translation/interacts with YTHDF2 to promote mRNA degradation
WTAP	Recruits METTL3 and METTL14 into the nuclear speckles
VIRMA	Recruits the MTC and correlates with polyadenylation cleavage factors, CPSF6 and CPSF5.
FTO	Removes m6A modification
HNRNPA2B1	Promotes primary miRNA processing
HNRNPC	Regulates mRNA abundance and splicing
RBMX	Regulates mRNA abundance and splicing
ZC3H13	Combines with WTAP to keep MTC in the nuclear speckles
ALKBH3	Removes m6A modification
ALKBH5	Removes m6A modification
EIF3A	Induces mRNA recruitment to the 43S PIC and detects the mRNA for AUG recognition.
IGF2BP1/2/3	Enhances the constancy and protein synthesis from mRNA
PCIF1	Recruits to the early elongation complex of RNAPII via interaction with POLR2A and mediates the formation of m6A(m) cotranscriptionally