Research Article

[Retracted] The Effect of Nonpharmacological Integrated Care Protocols on Patients with Fatigue Undergoing Hemodialysis: A Randomized Controlled Trial

Table 3

Comparison of the difference values between the two groups pre- and postintervention ().

IndicatorsMedian ()Median ()Comparison ( value)
Intervention group ()Control group ()

Overall fatigueag2.25 (1.43, 3.43)0.50 (0.27, 1.05)≤0.001
Mental fatigueg1.31 (0.51, 2.89)0.64 (0.22, 1.12)≤0.001
Muscular fatigueg2.06 (1.25, 3.00)0.79 (0.24, 1.18)≤0.001
CRP (mg/L)1.84 (-2.22, 8.30)1.31 (-3.41, 4.37)0.213
PTH (pg/mL)22.66 (-27.37, 64.01)9.40 (-26.38, 67.50)0.656
Hb (g/L)8.00 (-2.00, 28.00)5.50 (1.75, 23.00)0.737
ALB (g/L)6.17 (1.13, 8.34)4.42 (1.72, 8.58)0.646
P (mmol/L)0.32 (-0.44, 1.01)-0.05 (-0.33, 0.29)0.185
Ca (mmol/L)0.18 (-0.06, 0.47)0.10 (-0.11, 0.30)0.138
Fe (μmol/L)3.19 (-2.19, 7.64)0.76 (-1.78, 4.66)0.188
SF (μg/L)25.36 (-12.38, 52.66)10.65 (-13.04, 29.16)0.301
TSATg8.03 (2.25, 14.87)2.06 (0.79, 2.89)≤0.001
Urea (mmol/L)h3.35 (-0.07, 11.73)1.62 (-3.47, 5.97)0.018
PSSSb6.00 (2.75, 6.00)5.00 (-16.00, 21.00)0.876
Intrafamilial support4.00 (2.00, 4.00)2.00 (0.00, 6.00)0.359
Extrafamilial support2.00 (-16.00, 16.00)2.00 (0.00, 2.00)0.965
Vitality on the SF-36h5.00 (1.00, 9.00)2.00 (2.00, 5.25)0.048
PQSIch4.00 (0.75, 6.00)1.00 (0.00, 3.00)0.002
Anxiety1.00 (-2.00, 4.00)1.00 (0.00, 1.00)0.616
Depressionh2.50 (0.00, 6.25)1.00 (0.00, 3.00)0.012
Overall behavioral self-managementdg16.50 (6.00, 19.25)6.50 (2.00, 12.00)≤0.001
Compliance with recommendations for sodium and protein intakeh3.00 (1.00, 5.00)1.00 (0.00, 4.00)0.001
Compliance with recommendations for liquid intakeh3.00 (1.00, 7.00)2.00 (0.00, 3.25)0.005
Compliance with recommendations for iron intakeg2.00 (0.00, 3.00)0.00 (0.00, 0.00)≤0.001
Self-monitoring of disease1.00 (0.00, 3.00)0.00 (0.00, 1.00)0.146
Developing good habits0.00 (0.00, 1.00)0.00 (0.00, 1.00)0.337
Protecting the internal fistula0.00 (0.00, 1.00)0.00 (0.00, 1.00)0.399
Maintaining personal health1.00 (0.00, 2.00)0.00 (0.00, 1.00)0.064
Seeking knowledge0.00 (-2.00, 3.00)0.00 (0.00, 1.00)0.877
Developing interests and hobbies0.00 (0.00, 1.00)0.00 (0.00, 0.00)0.424
Compliance with medication regimen0.00 (0.00, 0.00)0.00 (0.00, 0.00)1

Abbreviations: CRP: C-reactive protein; PTH: parathyroid hormone; Hb: hemoglobin; ALB: albumin; P: phosphorus; Ca: calcium; Fe: ferritin; SF: serum ferritin; TSAT: serum transferrin saturation; SF-36: 36-Item Short-Form Health Survey; PSSS: Perceived Social Support Scale; PSQI: Pittsburgh Sleep Quality Index. The continuous within-group variables are reported as the of difference values between pre- and postintervention measurements; the categorical variables are expressed as frequencies after the intervention. Bold values are statistically significant ( or ). aTotal fatigue scores can range from 0 to 10, of which 0, 1–3, 4–6, and 7–10 indicate no symptoms, mild symptoms, moderate symptoms, and severe symptoms, respectively. bTotal support scores can range from 12 to 84, with higher scores indicating better perceived social support. cTotal scores can range from 0 to 21, with ≤7 points indicating normal sleep and >7 points indicating a sleep disorder. dTotal scores can range from 25 to 100, with a higher score indicating better behavioral self-management. gComparison of the difference values of pre- and postintervention between groups, . hComparison of the difference values of pre- and postintervention between groups, .