[Retracted] Single-Cell Transcriptome Analysis Reveals the Importance of IRF1/FSTL1 in Synovial Fibroblast Subsets for the Development of Rheumatoid Arthritis

Figure 4

Variance analysis and functional pathway analysis. (a) Volcano plot showing differentially expressed genes between RA and OA groups. Among them, IRF1 expression is up-regulated in RA relative to that in OA. (b–c) Pathway enrichment analysis showing (b) up-regulated and (c) down-regulated pathways in RA. (d) Analysis of gene expression differences between RA and OA groups at the single-cell level. Yellow dots represent genes up-regulated in RA, and dark blue dots represent genes up-regulated in OA. Large diameter dots represent genes that are differentially expressed between the two groups. (e) Heat map showing the expression of top 20 up-regulated and top 20 down-regulated genes of the RA and OA groups.

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